Its risky because with no load on the engine you really don't know for sure how far the 'stat opened, if at all. In fact one year I tried an experiment. I had AF in the engine after winterizing it. In the spring I ran it up on the water hose for 20 min. Then pulled the block drains to see what came out, water or AF....well....the AF poured in months earlier, was still in there even after running it for 20 min. So just be aware of that....the stat functions as a gate valve letting water out of the engine, only when it gets hot enough to make the stat open. Sometimes you can tell because the big hose from the stat housing to the circulating pump gets hot, or the hoses that feed the manifolds will get warmer than when you first started it because now the hot water leaving the block is exiting via the stat and mixing with the cool water being pumped in by the impeller...
The only way I'd use the suck up the AF method, is if you drained it before, or, if the engine had a heat exchanger on it and you just wanted to get AF in the raw water side.