Any acid will be rough on anodes. Acids take electrons and anodes give electrons, that's why they interact so actively. I left my anodes in, mostly because after 20 years in salt I thought trying to take them out was going to do more damage (broken bolts, etc..). If the sand is packed in there, especially after some time, I really doubt trying to get it out with water pressure is going to work. Hopefully a chemical will remove whatever is holding it up in there (maybe the passage is restricted by build up), or worst case is probably physical removal. But I would personally try a rinse with a strong descaler like Rydlyme before anything else.