Not in the way as on a carbed engine but lean looking plugs might lead me to have injectors cleaned if not done for a long time and check fuel pump pressure.
What I love about carbs, they are infinitely tuneable, not only that you have choice of Edelbrock, Holley/Quickfuel, or Quadrajet (if you have a good original core like I do) 2bbl, 4bbl whatever you want. Yes they take more time to get right but once you understand them, they are easier to live with because of the wide availability of parts. Much less expensive to keep going.