Why not? The manual gives you a starting point for the adjustments, to get it close enough to start the engine, then you have to dial in the adjustments with some fine tuning. 2 turns out (or whatever the spec is) is a starting point, but you will have to turn the screws in-out a bit to get it running perfect. Idle mixture screws to get it idling smooth (rich/lean), then the idle speed adjustment to fine tune in the idle speed higher/lower.
I set the idle speed, then the idle mixture, then go back and double check the idle speed, then the mixture, etc. It's a balancing act as the idle mixture settings can affect idle speed, and if you change the idle speed it can affect the idle mixture. You have to "dial it in"
(BTW, I've never worked on a VP AQ131, but have tuned lots of carbs)