spark/ignition is not related to the mixture adjustment (initial h.s. needle setting, btw, is about 1 turn open. When making final adjustment at speed, it’s likely to be less than 1.)
I’m not sure what ignition parts were replaced, but suggest you open it up and review. Wires should be 7mm with a wire core, not automotive wires. The spikes of the spring clips in the plug boots need to be in solid contact with the core wire. Coils likewise need to be in solid contact with the cores. In addition, be sure the coils are perfectly flush with the machined edges of mounting posts (establishes the flywheel air gap.)