The first time you use the E10, it may well loosen and old dirt in the fuel system. You may need to change filters, or the carb may clog.
After that, when the fuel system is cleaned by the e10, you shouldn't have any trouble with the E10 fuel.
On a small motor like that, that you are not going to use for some weeks, run her out of fuel or drain the carb.
Most only use a fuel stabilizer over the winter, and some use it all the time. I use it for winter storage, along with the usual storage items like fogging oil, new gear oil and new grease in the fittings.
E10 is not an issue, IMO, despite what some believe. It absorbs water in the fuel, which is good, and the motor runs just fine on it.