I think we need more info. Number of family left behind, ages? Time expected in new position? Locale? Years to retirement, what does this do to that? etc. etc.
Also depends on what you mean by "cross country". There is a good reason there are 15 Million of us here in So Cal. Easy to dismiss until you've lived through a full year. We have the best weather in the world, almost without challenge. But that all assumes it's So Cal. Add in that the state is broke, and we have other issues, and what you think of winter, summer. Do you like visitors? I know a number of Brits that have done it, and they wouldn't go back, and that was for even money, so it just depends on all of the factors. They get a steady flow of visitors winter and summer
What about boating? Type? Walkarounds are very popular here. Some decent fishing. Lol.
Phoenix? Bay Area? Seattle? Portland? All have their pluses and minuses.