Hey Jason,
A real quick guide to the "sweet spot" - if you will. Get her up on plane. Trim it out for your optimum running then just start to throttle back. What you're looking for is the boat's ability to stay in that configuration using the least amount of rpm's possible.
Now, the worst thing you could do would be to have the bow really high - that's pushing the boat and extremely hard on the motor ( not to mention your fuel consumption ).
Don't even look at your tach - use your ears. Your motor will tell you when it's happy.

Do remember that with extra weight onboard you will need to push her a little harder to keep on plane. But then again, it's all relevant isn't it ?