So my thoughts are if there is any way to upgrade to an "LT" light truck tire you are going to be a thousand miles ahead. A "ST" special trailer tire is a lower grade lower cost tire that's not designed to support the forces put on a tire by vehicle cornering, burnouts, hard braking, skidpad, etc. It just rolls with a load under very little side pressure and does some light braking if you have that but that's just an assist, the tow vehicle does most of the stopping. Obviously the common hub sizes and commonly available trailer wheels and fenders aren't condusive to a LT-sized tire. Also a LT tire is likely a $250 tire instead of a $100 tire (like an ST). But just saying here, the trailer tires are not up to the same standard and are denoted as such. Personally I prefer radials. I lower the tire pressure to around 25 psi when removing and then storing for months at a time to reduce oxygen pressure on the inside of the tire. I think under load the sidewall flexing builds heat in the tire as does high speeds or higher loads (closer to the max printed load). Tire pressure helps with sidewall flexing but also puts the case of the tire under greater hoop stress in two directions where its more prone to a catastrophic blowout, especially if that's catalyzed by a sharp edge of an object or some road feature struck at speed. As far as brands, I have always laid my money on Michelins and had excellent results in around 6 different vehicles. That said, Michelin doesn't make a boat trailer tire in my size so I elected to go with Carlisle Radials and not enough miles or years to make any kind of judgement whatsoever. I believe in general you get what you pay for although sharp objects can kill any price point tire. I keep speeds down to 65mph when interstate towing and allow time to get where I'm going. Spares are almost worth their weight in gold as is hub maintenance. There are tradeoffs on everything and no hard and fast rules but there are some trends you can understand and follow.